Well, earlier tonight, I found out what may happen if you forget to do that. You might suffer side effects. I wrote a li'l song about it:
Well bless-a my soul, what's-a wrong with me?
I'm itchin' like a man on a fuzzy tree!
My skin is prickly an' a-flushed and hot
I'm on Niaspa
Uh-uh-huh... uh-huh... heyyyyy!
I'm feeling better now, but I guess I better not forget the aspirin-an-hour-before trick again.